Coroner Issues Urgent Alert Over Rising Threat of Nitazene Opioids.

Dangerous ‘nitazene’ opioids are on the rise in Ireland and researchers are worried. Be aware!

An Ireland coroner has issued a grave warning regarding the escalating dangers posed by nitazenes, latter a ‘new to the market’ and a highly potent group of synthetic opioids, now increasingly linked to sudden deaths across the region.

The alert follows the inquest into the death of 33-year-old Portadown man, Mr Jay Woolsey, who died in August 2024. During the hearing, the coroner stressed that nitazenes are far stronger than previously understood, in some cases hundreds or even thousands of times more potent than morphine. Since late 2023, these substances have been entering the drug market in Ireland and at speed.

Authorities warn that the potency of nitazenes varies significantly, with some similar in strength to heroin while others far exceed the power of fentanyl. This inconsistency creates a dangerously high risk of accidental overdose. Compounding the threat, nitazenes have been identified in drugs typically seen as non-opioid substances, including MDMA, ketamine and benzodiazepines, thus placing unsuspecting users at severe risk.
Note: Fentanyl test strips do not detect nitazenes.

The physical effects mirror those of other opioids and can include:

1. Euphoria or a dreamlike state.
2. Unresponsiveness or loss of consciousness.
3. Itchiness.
4. Severe nausea or vomiting.
5. Slow or difficult breathing.
6. Blue lips or fingertips.
7. Cold, clammy skin‘
8. Pinpoint pupils.

To date, ten additional nitazene-related deaths have been recorded across the North of Ireland, many involving polydrug use. The coroner noted that families are often unaware that loved ones are sourcing dangerous substances online or via the dark web.

Public Health Agencies and police have reiterated serious concerns about nitazenes being mixed with heroin and other drugs, often without users’ knowledge, sharply increasing the potential for fatal overdose.

Public health agencies and support services are now being urged to take immediate action, including:

• Strengthening early-warning systems and enhancing monitoring of emerging synthetic opioids, ensuring rapid information-sharing across health, Gardaí, justice and community sectors.
• Improving multi-agency cooperation to enable fast, coordinated responses to overdose spikes and new drug threats.
• Expanding rapid-access treatment options and ensuring families affected by overdose receive timely, appropriate support.
• Issuing clear and consistent public alerts when nitazenes are detected and promoting practical harm-reduction guidance for drug users and their families.
• Making nitazene test strips available through harm-reduction and outreach services to help identify contamination and prevent further deaths.

Authorities are urging communities to remain vigilant and to seek immediate medical help if signs of opioid overdose are present.